BioIntegral Surgical manufactures cardiac and vascular implants made from all-biological
materials using the No-React® treatment.
No-React® is a proprietary detoxification of glutaraldehyde-treated tissue. 17 years
of clinical experience with No-React® devices shows reduced toxicity, enhanced biocompatibilty,
lower rates of infection, adhesion, calcification, and the promotion of endothelial
The products are engineered from both a material and design perspective to enhance
durability, biocompatibility, and ease of implantation.
The design philosophy is to solve structural heart issues by minimizing compromises
to the patient or surgeon required by alternative devices or techniques. More consistent,
simplified, and repeatable operative outcomes help to reduce morbidity and mortality.
BIOINTEGRAL PRODUCT RANGE
No-React® Treatment - Benefits
17 years of clinical experience with No-React® devices shows
Lower rates of Infection
Lower rates of Calcification
Promotion of Endothelial Lining
BioIntegral Surgical's No-React® technology has an extensive medical history.
Over the past 17 years, No-React® devices have been implanted in over 100,000 patients